TEMPORAL REQUIREMENTS OF THE FRAGILE X MENTAL RETARDATION PROTEIN IN MODULATING CIRCADIAN CLOCK CIRCUIT SYNAPTIC ARCHITECTURE

Temporal requirements of the fragile X mental retardation protein in modulating circadian clock circuit synaptic architecture

Loss of fragile X mental retardation 1 (FMR1) gene function is the most common cause of inherited mental retardation and autism spectrum disorders, characterized by attention disorder, hyperactivity and disruption of circadian activity cycles.Pursuit of effective intervention strategies requires determining when the FMR1 product (FMRP) is required

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Beyond extraction accuracy: addressing the quality of geographical named entity through advanced recognition and correction models using a modified BERT framework

In the realm of geospatial services and applications, the accuracy of address information is of utmost importance.Traditional methods of data collection, being both labor-intensive and costly, have prompted researchers to turn to Volunteered Geographic Information (VGI) for the extraction of Geographical Named Entity (GNE).Notwithstanding, prior st

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Urgent total pancreatoduodenectomy for profuse gastro-intestinal bleeding caused by renal cancer metastases to the pancreas

Renal cancer (RC) can spread to different organs, Pedal Return Cable metastatic damage of the pancreas is quite rare.But, in contrast of primary and other metastatic malignant tumors, pancreatic RC metastases can be resectable in 80 % of cases with nearly 90 % 5-year survival rate.Pancreatic oncologic surgery includes 3 different types of resection

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